Pyridinium Para Toluene Sulfonate (PPTS) is a mild, organic-soluble acidic catalyst formed from pyridine and p-toluenesulfonic acid. It is preferred in organic synthesis where selective protection or deprotection of functional groups is required without damaging acid-sensitive moieties.
| CAS Number | 24057-28-1 |
| Chemical Formula | C12H13NO3S |
| Molecular Weight | 251.30 g/mol |
| Appearance | White to off-white crystalline powder or colorless crystals |
| Melting Point | 116 – 120 °C (standard; up to 120 °C for high purity) |
| Purity | ≥ 98.0% or ≥ 99.0% |
| Solubility |
Soluble in water, methanol, ethanol, acetone, and dichloromethane (DCM) |
| Sensitivity |
Moisture-sensitive and hygroscopic. Exposure to air may cause clumping and reduced catalytic activity. |
| Packing |
Laboratory packs: 100 g, 500 g bottles Industrial packs: 25 Kg HDPE containers or fiber drums with PE liners |
| Synonyms |
PPTS, Pyridinium tosylate, p-Toluenesulfonic acid pyridine salt |
| Uses |
Used as a mild, organic-soluble acidic catalyst for selective protection and deprotection of functional groups in sensitive organic synthesis. |
