4-Propyl-o-phenylenediamine (4-Propylbenzene-1,2-diamine) is a substituted aromatic diamine used as a critical building block in the synthesis of heterocyclic compounds, particularly in the production of veterinary anthelmintics.
| CAS Number | 66608-52-4 |
| Chemical Formula | C 9 H 14 N 2 |
| Molecular Weight | 150.22 g/mol |
| Appearance | Grayish-white to light brown crystalline solid or flakes |
| Melting Point | 68 – 72 °C |
| Purity | ≥ 98.0% (typically by GC or HPLC) |
| Solubility | Soluble in Methanol, Ethanol, and Chloroform; slightly soluble in water |
| Safety Information |
Classified as Toxic and Harmful (GHS06/GHS07); it is harmful if swallowed or absorbed through the skin, causes serious eye irritation, and is a suspected mutagen, requiring handling in a controlled laboratory environment with full PPE. |
| Packing |
Laboratory: 25g, 100g, 500g amber glass bottles; Industrial: 25 kg fiber drums with double-layered PE liners to prevent oxidation. |
| Synonyms | 4-Propyl-1,2-phenylenediamine, 4-Propyl-1,2-diaminobenzene |
| Uses |
4-Propyl-o-phenylenediamine is primarily used as a key intermediate in the pharmaceutical industry for the synthesis of benzimidazole-class anthelmintic drugs, such as Albendazole and Oxibendazole. Nitroscanate) and benzothiazole derivatives.. |
