The term refers to a specific chemical compound, N-(pyridine-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide, which is an intermediate used in the synthesis of the cancer medication acalabrutinib
| CAS Number | 1383385-64-5 |
| Chemical Formula | C18H21BN2O3 |
| Molecular Weight | 324.19 g/mol |
| Appearance | White to off-white solid |
| Purity | Typically ≥ 97% |
| Packing |
Powder form: 25 Kg HEDP bag with 2 inner liners (5-layer protected packaging) |
| Synonyms |
N-(Pyridin-2-yl)-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)benzamide, N-2-Pyridinyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide, 4-(2-Pyridylcarbamoyl)phenylboronic acid pinacol ester, Benzamide, N-2-pyridinyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, Acalabrutinib Intermediate 2 |
| Shelf Life | Up to 24 months when stored under recommended conditions. |
| Uses |
Used as a key intermediate in the synthesis of Acalabrutinib, a Bruton’s tyrosine kinase (BTK) inhibitor for the treatment of blood cancers such as mantle cell lymphoma and chronic lymphocytic leukemia. |
