Apixaban intermediate Ehtyl(2z)-chloro-[(4-methoxyphenyl)Hydrazono]ethanoate

The name Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoate refers to a key chemical intermediate
used in the synthesis of the anticoagulant drug Apixaban.

CAS Number 27143-07-3
Chemical Formula C11H13ClN2O3
Molecular Weight 256.69 g/mol
Appearance White, off-white, or yellow to dark yellow crystalline powder
Melting Point 94 – 101 °C
Application Key pharmaceutical intermediate used in the industrial
synthesis of the anticoagulant drug Apixaban.
Storage Conditions Store sealed in a dry environment at cool temperatures,
preferably 2 – 8 °C.
Packing Powder form: 25 Kg HEDP bag with 2 inner liners
(5-layer protected packaging)
Synonyms (Z)-Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate,
Chloro[(4-methoxyphenyl)hydrazono]acetic acid ethyl ester,
Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]acetate,
Ethyl (2Z)-2-chloro-2-[2-(4-methoxyphenyl)hydrazin-1-ylidene]acetate,
Apixaban intermediate
Shelf Life Up to 2 years when stored under recommended conditions.
Uses Primarily used as a key pharmaceutical intermediate in the
synthesis of Apixaban for anticoagulant therapy applications.

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