Canagliflozin Intermediate 2-(5-iodo-2-methylbenzyl)-5-(4-flourophenyl) thiophene

The term refers to a specific chemical compound, 2-(5-iodo-2-methylbenzyl)-5-(4-fluorophenyl)thiophene, with CAS number 898566-17-1, which is an intermediate in the synthesis of the medication Canagliflozin. Canagliflozin is an SGLT2 inhibitor used to treat type 2 diabetes, and this compound is a crucial building block in its manufacturing process.


CAS Number 898566-17-1
Chemical Name 2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene
Chemical Formula C18H14FIS
Molecular Weight 408.27 g/mol
Appearance White to off-white powder or crystalline solid
Purity Typically ≥ 95% (higher purities available on request)
Packing Powder form: 25 Kg HEDP bag with 2 inner liners
(5-layer protected packaging)
Synonyms 2-(4-Fluorophenyl)-5-(5-iodo-2-methylbenzyl)thiophene,
Thiophene, 2-(4-fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]-,
Canagliflozin Iodo Impurity
Uses Used as a key intermediate in the synthesis of Canagliflozin,
a medication for the treatment of Type 2 diabetes.

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