Iodobenzene (Phenyl Iodide) is a foundational organoiodine compound that acts as a highly reactive aryl halide. It is widely used in modern organic synthesis for constructing complex molecules through metal-catalyzed coupling reactions.
| CAS Number | 591-50-4 |
| Chemical Formula | C6H5I |
| Molecular Weight | 204.01 g/mol |
| Appearance |
Clear, colorless to pale yellow liquid (may darken to reddish-brown on prolonged storage) |
| Melting / Boiling Point |
Melting Point: −31 °C Boiling Point: 188 °C |
| Purity | ≥ 98.0% or ≥ 99.0% |
| Solubility |
Soluble in ethanol, ether, and chloroform; insoluble in water |
| Safety Information |
Classified as Harmful (GHS07) and combustible. Causes skin and eye irritation and is harmful if swallowed. Handle in a fume hood with appropriate chemical-resistant gloves and eye protection. |
| Packing |
Laboratory packs: 100 g, 500 g, 1 Kg amber glass bottles Industrial packs: 25 Kg to 200 Kg fluorinated HDPE drums or stainless steel containers to prevent light-induced degradation |
| Synonyms |
Phenyl iodide, Benzene iodide, Monoiodobenzene |
| Uses |
Primarily used as a versatile arylating agent in organic synthesis for forming carbon–carbon and carbon–heteroatom bonds in Suzuki, Heck, and Sonogashira coupling reactions. It is also a key precursor for the preparation of hypervalent iodine reagents. |
