Methyl-4-iodobenzoate is an organic building block widely used in modern synthetic chemistry. It is especially important as a substrate for palladium-catalyzed cross-coupling reactions in pharmaceutical and advanced material synthesis.
| CAS Number | 619-44-3 |
| Chemical Formula | C8H7IO2 |
| Molecular Weight | 262.04 g/mol |
| Appearance | White to off-white to light yellow crystalline powder |
| Melting Point | 113 – 117 °C |
| Purity | ≥ 98.0% or ≥ 99.0% |
| Solubility |
Soluble in chloroform, methanol, and ethyl acetate; insoluble in water |
| Safety Information |
Classified as an irritant (GHS07). May cause skin, eye, and respiratory irritation. Handle using standard laboratory PPE and avoid inhalation of dust. |
| Packing |
Laboratory packs: 5 g, 25 g, 100 g amber glass bottles Industrial packs: 25 Kg fiber drums with light-resistant liners |
| Synonyms |
4-Iodobenzoic acid methyl ester, Methyl p-iodobenzoate |
| Uses |
Primarily used as an intermediate in organic synthesis for Suzuki, Heck, and Sonogashira coupling reactions. Commonly applied in the synthesis of pharmaceuticals, liquid crystals, and other high-value specialty chemicals. |
