4-Iodoaniline, also known as para-iodoaniline, is a highly reactive aromatic amine that combines a primary amino group with an aryl iodide. This dual functionality makes it a valuable building block in advanced pharmaceutical and material chemistry.
| CAS Number | 540-37-4 |
| Chemical Formula | C6H6IN |
| Molecular Weight | 219.02 g/mol |
| Appearance | White to off-white or light brown crystalline powder or needles |
| Melting Point | 60 – 63 °C |
| Purity | ≥ 98.0% or ≥ 99.0% |
| Solubility |
Soluble in ethanol, ether, and chloroform; slightly soluble in water |
| Safety Information |
Classified as Toxic (GHS06) and Harmful. Causes skin and eye irritation, is toxic if swallowed or in contact with skin, and prolonged exposure may affect blood (methemoglobinemia). Handle only with appropriate PPE and adequate ventilation. |
| Packing |
Laboratory packs: 25 g, 100 g, 500 g amber glass bottles Industrial packs: 25 Kg fiber drums with light-shielding PE liners |
| Synonyms |
p-Iodoaniline, 4-Aminoiodobenzene, 1-Amino-4-iodobenzene |
| Uses |
Primarily used as a key intermediate in the synthesis of pharmaceuticals, liquid crystals, and organic semiconductors. Acts as a bifunctional linker in palladium-catalyzed Suzuki, Heck, and Sonogashira cross-coupling reactions. |
