4-iodo-1-chloro-[(4-ethoxyphenyl) methyl benzene
This halogenated aromatic compound is used primarily as an intermediate in the synthesis of Dapagliflozin. Dapagliflozin is a drug prescribed for the treatment of type 2 diabetes.
| CAS Number | 1103738-29-9 |
| Chemical Formula | C15H14ClIO |
| Molecular Weight | 372.63 g/mol |
| Appearance | White to off-white solid |
| Melting Point | 62 – 64 °C |
| Boiling Point | 411.2 ± 40.0 °C at 760 mmHg (predicted) |
| Density | 1.531 ± 0.06 g/cm³ (predicted) |
| Flash Point | 202.5 ± 27.3 °C |
| Storage Conditions | Store at 2 – 8 °C in a sealed, dry, and dark place |
| Packing |
Powder form: 25 Kg HEDP bag with 2 inner liners (5-layer protected packaging) |
| Synonyms |
1-Chloro-2-[(4-ethoxyphenyl)methyl]-4-iodobenzene, 4-Iodo-1-chloro-2-(4-ethoxybenzyl)benzene, Benzene, 1-chloro-2-[(4-ethoxyphenyl)methyl]-4-iodo-, 4-(5-Iodo-2-chlorobenzyl)phenyl ethyl ether, 5-Iodo-2-chloro-4′-ethoxydiphenylmethane, SOTA-006, EGT-OET(I), EOS-61384 |
| Shelf Life |
Typically 1 to 3 years depending on manufacturer, when stored under recommended conditions. |
| Uses |
Used as a key pharmaceutical intermediate in the synthesis of SGLT2 inhibitors such as Dapagliflozin and Sotagliflozin for the treatment of Type 2 diabetes. Also used in research, development, and as an analytical reference standard. |
